Cytisine

What is Cytisine

Cytisine is an alkaloid compound that is found naturally in various plant species like golden rain acacia and Scotch broom. The most common source of cytisine is from the Cytisus scoparius plant.

Cytisine has been used for centuries in eastern European folk medicine as a remedy for improving breathing function. More recently, it has been developed and studied as a treatment for nicotine addiction and smoking cessation.

Cytisine powder provides a purified and concentrated supplemental form of cytisine. It is a fine crystalline powder that is white to off-white in color. It has a mildly bitter taste which can be masked when dissolved into a beverage.

As a nicotinic acetylcholine receptor agonist, it mimics the effect of nicotine on brain receptors. This helps curb cravings and ease withdrawal symptoms when quitting smoking. However, cytisine does not carry the same cardiovascular and cancer risks as nicotine.

It has several advantages over other nicotine cessation aids: - Natural plant-derived compound - Less expensive than nicotine patches or gum - Low toxicity and side effects - Long-term safety demonstrated in studies - Higher efficacy rates for quitting smoking.

Chemical Composition

Specifications

Certificate  of  Analysis

Our Advantages

1. Hubei Sanxin Biological Technology Co., Ltd. is a Cytisine Powder supplier and manufacturer,
2. The content of natural Cytisine we provide can reach 98%, and we have a number of international certification systems: Halal, Kosher, FDA, ISO9001, PAHS Free, NON-GMO, SC.
3. We could offer a stable and sufficient supply of raw materials, and the delivery time is stable.
4. In addition, we have a professional production line, and the production capacity is 20 tons per year. More than 23 patents for manufacturing plant extract have been authorized to Sanxin Biotech.
5. OEM offered.
6. We have a strict quality control system and stable supply chains to support our products.

Functions

The main mechanisms of action and effects of cytisine powder are:

Nicotinic Receptor Agonist

Cytisine activates α4β2 nicotinic acetylcholine receptors which are the primary spots of nicotine dependence . This provides relief from cigarette jones and nicotine pullout symptoms including perversity, anxiety, restlessness, and increased appetite.

Dopamine Release

By stimulating nicotinic receptors, cytisine triggers the release of dopamine in the brain's reward system similar to nicotine. This dopamine release rewards and reinforces non-smoking behavior.

Reduced Smoking

In clinical trials, It has been shown to help smokers quit, remain abstinent, and reduce overall cigarette consumption. It is an effective aid when combined with counseling.

Improved Breathing

By promoting smoking cessation, cytisine improves respiratory function and reduces coughing, shortness of breath, and other smoking-related breathing problems.

Cardiovascular Benefits

Quitting smoking and nicotine with the help of cytisine powder decreases heart rate, blood pressure, risk of heart attack and stroke, and other cardiovascular benefits.

Applications of Cytisine

Cytisine is an alkaloid compound found naturally in plants like golden rain acacia and Scotch broom. While toxic in high doses, cytisine has pharmacological effects that have led to applications across pharmaceutical, tobacco, food and beverage industries.

Pharmaceutical Industry

The major pharmaceutical use of cytisine is as a smoking cessation aid. Cytisine acts as a partial agonist on nicotinic acetylcholine receptors, with similar effects to nicotine. This makes it useful for managing nicotine cravings and withdrawal during smoking cessation.

Several countries have approved cytisine drugs as non-prescription smoking cessation aids under brand names like Tabex, Sopharma and Desmoxan. These provide an alternative to nicotine replacement therapies.

In addition to smoking cessation, it has been investigated for treating alcohol dependence, obesity, and neurological conditions like Parkinson’s and Alzheimer’s disease, though more research is needed.

Tobacco Industry

While toxic at high levels, low concentrations of cytisine have been used by the tobacco industry to enhance the effects of nicotine in cigarette products. By adding cytisine, lower amounts of nicotine may be needed while still promoting addiction.

However, many countries now prohibit additive use in tobacco products other than what is essential to manufacturing. Due to its risks, it has been banned as a tobacco additive in some regions.

Food and Beverage Industry

Cytisine has been utilized as a flavoring agent in certain food and beverage products. It provides a distinctive, tea-like flavor. However, there are limits on allowable cytisine concentrations given its toxicity in higher amounts.

The bitter, complex taste provided by cytisine led to its use in vermouth, bitters, absinthe and some soft drinks for flavor enhancement. However, expanded use requires caution due to the narrow window between desired flavor effects and potential toxicity.

Pesticide Production

Cytisine's mechanism of action involves binding to nicotinic receptors, similar to neonicotinoid pesticides used in agriculture. Chemical analogs based on cytisine’s core structure have been investigated as insecticides given their targeted effects on insect nervous systems.

However, cytisine-derived compounds have seen limited commercial use as pesticides so far. More research is needed to develop safe, potent options that provide advantages over existing insecticide classes.

Animal Healthcare

At very low dosages, cytisine has been studied for reducing pain sensitivity in dogs. However, veterinary use remains highly limited due to the narrow therapeutic index and availability of safer pain medications.

Cosmetics

While not a common application, some plant-derived extracts containing cytisine have occasionally been included in topical products like creams and soaps for purported skin care benefits. However, cosmetic use remains very minimal given limitations around the allowable concentration of cytisine for topical application.

Flow Chart

Packing And Shipping

● Fast lead time, with a professional freight forwarder;

● Fast service response to customers' orders;

●  25kgs/drum, Double polyethylene bags inside, and high-quality standard carton drum outside.

Certificates

We have professional product certifications and technical invention patents, including Kosher certification, FDA certificate, ISO9001, PAHS Free, HAlAL, NON-GMO, SC.

Exhibition

We have participated in SUPPLYSIDE WEST. Our products are exported to more than 30 countries including the United States, India, Canada, Japan, and so on.

Our Factory

We have perfect and mature production technology. “Filter Tank Used In The Production Process of Resveratrol”, “Method of Producing Resveratrol with Fresh Polygonum Cuspidatum”, “High-Quality Low-Temperature Concentration Tank”, “Method of Preparing Resveratrol Extract by Microbial Fermentation Technology”, all of them have obtained national invention patents.

We are Cytisine powder manufacturers and suppliers, if you need please contact us at Email: nancy@sanxinbio.com.

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