What is the Nicotinamide Riboside CHloride Powder used for?

Specification Sheet

Nicotinamide Riboside Chloride Powder (abbreviated as NR-CI) is the precursor of an important coenzyme, also known as Vitamin B3. This coenzyme is Nicotinamide adenine dinucleotide (NAD+, also known as coenzyme I). It is a coenzyme that transmits protons (more accurately, hydrogen ions) and appears in many metabolic reactions of cells. The coenzyme is involved in the breakdown of compounds such as proteins, carbohydrates, and fats, and is essential for human life activities. As cells age or become diseased, their number will decrease. Therefore, supplementation of Nicotinamide riboside can increase the content of this coenzyme (NAD+) and improve the basic metabolic activity of cells, thus significantly improving cell vitality and improving various physiological functions of the human body.

We have professional production line and have the production capacity of Nicotinamide Riboside Chloride powder 20tons per year and more than 23 patents for manufacturing of plant extract.We have been on this line for 13 years.

Specification Sheet

Product Name	Nicotinamide riboside chloride(NR-CI)
CAS NO.	23111-00-4		Produce Date		2024.09.10
Batch NO.	SX202409110		Quantity		200kg
Test Date	2024.09.13		Reference		In House
Expiry Date	2026.09.09		Packing		20kq/drum
Test Item		Specifications		Test Result
Appearance		White or off-white powder		Off-white powder
Identification		Corresponds to the reference		Conforms
Solubility		Freely soluble in water, practically insoluble in n-heptane		Conforms
Assay (HPLC)		>98%		99.10%
Purity (by HPLC,% area)		>99%		99.33%
Water content		<1.0%		0.22%
Related substances		Nicotinamide<2.0%		0.15%
		Single impurity<0.5%		0.03%
		Total impurities^2.0%		0.19%
Enantiomer		s0.5%		Not Detected
Methanol		20.3%		0.11%
Ethanol		20.5%		0.003%
Heavy metals		wIO.Oppm		Conforms
As		<1.0ppm		<1.0ppm
Pb		<3.0ppm		<1.0ppm
Cd		wl.Oppm		Not Detected
Hg		sO.Ippm		Not Detected
Total microbial count		41000 cfu/g		Conforms
Molds & Yeasts		$100 cfu/g		Conforms
Escherichia coli		w10 MPN/g		Not Detected
Staphylococcus aureus		Negative		Not Detected
Pseudomonas aeruginosa		Negative		Not Detected
Conclusion		The product meets In-house requirements

Functions

1. Boosts NAD+ Levels

One of the primary functions of Nicotinamide Riboside is to increase NAD+ levels in the body. NAD+ is essential for energy production, DNA repair, and overall cellular function. As we age, NAD+ levels naturally decline, which is associated with various age-related health issues. By increasing NAD+ levels, NR may help counteract some of the effects of aging and promote cellular vitality.

2. Supports Cellular Energy Production

NAD+ plays a critical role in cellular metabolism, particularly in the mitochondria, where it is involved in the production of ATP (adenosine triphosphate), the body's primary energy currency. Nicotinamide Riboside helps enhance this process, supporting overall energy levels, physical performance, and endurance.

3. Improves Metabolic Health

Nicotinamide Riboside has been shown to support metabolic health by improving insulin sensitivity and regulating glucose metabolism. Higher NAD+ levels may help prevent or manage conditions like obesity, type 2 diabetes, and metabolic syndrome, by promoting healthier fat metabolism and reducing inflammation.

4. Promotes Healthy Aging

As an NAD+ booster, Nicotinamide Riboside is often associated with anti-aging benefits. Increased NAD+ levels may help activate sirtuins, a group of proteins that play a role in regulating the aging process, protecting DNA, and reducing oxidative stress. This can potentially slow down the cellular aging process, improve skin health, and enhance longevity.

5. Enhances Cognitive Function

Research suggests that Nicotinamide Riboside may support brain health by increasing NAD+ levels in neural cells. This can potentially improve cognitive function, support memory, and protect against age-related cognitive decline and neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.

6. Supports Heart Health

Nicotinamide Riboside may have a positive effect on cardiovascular health by improving mitochondrial function in heart cells and promoting healthy blood vessel function. It may also help reduce inflammation and oxidative stress, which are key contributors to heart disease.

7. Promotes Muscle Health and Recovery

Nicotinamide Riboside has been shown to support muscle function by improving mitochondrial efficiency and energy production in muscle cells. This can help enhance muscle endurance, strength, and recovery after exercise, potentially aiding in fitness and athletic performance.

 

Application

 

1. Anti-Aging and Longevity

Nicotinamide Riboside Powder is widely used in anti-aging supplements due to its ability to increase NAD+ levels. NAD+ plays a critical role in cellular repair, energy production, and maintaining the health of mitochondria. As NAD+ levels naturally decline with age, NR is believed to help slow down the aging process by enhancing cellular function, DNA repair, and improving overall vitality.

2. Metabolic Health and Weight Management

NR is utilized in metabolic health products, particularly those targeting weight loss and insulin sensitivity. By boosting NAD+ levels, NR supports better fat metabolism, glucose regulation, and improved mitochondrial function, which can help in the prevention or management of conditions like obesity, type 2 diabetes, and metabolic syndrome.

3. Exercise and Physical Performance

Nicotinamide Riboside is increasingly used in sports nutrition and fitness supplements to improve muscle endurance, recovery, and exercise performance. By enhancing NAD+ levels, it supports better mitochondrial function, leading to improved energy production during exercise. This can help athletes and fitness enthusiasts enhance their physical performance and reduce recovery time after intense workouts.

4. Cognitive Health

NR is being explored for its potential in promoting brain health and protecting against neurodegenerative diseases such as Alzheimer's and Parkinson’s. By increasing NAD+ levels in neurons, NR may help improve cognitive function, memory, and focus, while also offering neuroprotective effects that may delay the onset of age-related cognitive decline.

5. Cardiovascular Health

Nicotinamide Riboside is applied in supplements aimed at heart health. Research suggests that NR may improve mitochondrial function in heart cells, reduce oxidative stress, and support better blood vessel function, potentially helping with conditions like hypertension, heart disease, and improving overall cardiovascular health.

6. Skin Health

NR's ability to enhance NAD+ levels may also have applications in dermatology. By improving mitochondrial function and reducing oxidative stress, Nicotinamide Riboside could support skin regeneration and anti-aging treatments, helping to reduce the appearance of fine lines and wrinkles, and improve skin texture.

7. Cellular Repair and Regeneration

NR has potential applications in promoting cellular repair and regeneration. By increasing NAD+ levels, it may help activate sirtuins, enzymes that regulate DNA repair and protect cells from stress. This can be particularly useful in applications aimed at supporting tissue recovery, wound healing, and overall cellular health.

8. Support for Chronic Diseases

Given its role in cellular energy production and mitochondrial function, Nicotinamide Riboside is also being studied for its potential in chronic disease management. It may help alleviate symptoms associated with conditions like chronic fatigue syndrome, fibromyalgia, and age-related degenerative diseases by improving energy production and reducing inflammation.

Flow Chart

 

Package

Our Certificate

We have professional product certifications and technical invention patents, including Kosher certification, FDA certificate, ISO9001, PAHS Free, HAlAL, NON-GMO, SC.

 

Our Exhibition

We have participated in SUPPLYSIDE WEST. Our products are exported to more than 30 countries including the United States, India, Canada, Japan, and so on.

Our Fatcory

We have perfect and mature production technology. “Filter Tank Used In The Production Process of Resveratrol”, “Method of Producing Resveratrol with Fresh Polygonum Cuspidatum”, “High-Quality Low-Temperature Concentration Tank”, “Method of Preparing Resveratrol Extract by Microbial Fermentation Technology”, all of them have obtained national invention patents.

We are Nicotinamide Riboside Chloride Powder  manufacturers and suppliers, if you need please contact us at Email: nancy@sanxinbio.com.

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