What is Matrine
Matrine is a quinolizidine alkaloid found abundantly in Sophora flavescens, a Chinese herb used traditionally for inflammatory conditions, viral diseases, cancer and cardiovascular disorders. As an isolated compound, matrine exhibits wide-ranging bioactivities that make it valuable across pharmaceutical, nutraceutical and agricultural industries.
Sophora flavescens contains various alkaloids including matrine, oxymatrine, sophoridine and oxysophocarpine. Of these, it is one of the primary components, making up 0.5-2.4% dry weight of the root extract.
Chemically, matrine consists of a quinolizidine ring structure that confers its biological effects.It has been shown to regulate vulnerable responses, inhibit excrescence growth, cover organs and demonstrate antiviral goods.
Matrine shows broadanti-inflammatory exertion by suppressing overproduction of seditious cytokines like TNF- nascence, IL- 1beta, IL- 6 and IL- 8. This helps manage inflammatory conditions without compromising immunity.
Additionally, matrine displays wide-spectrum antiviral effects against hepatitis B virus, coxsackie virus, Japanese encephalitis virus, herpes viruses and others. It inhibits viral attachment, entry and replication in host cells.
Matrine also induces cancer cell apoptosis, restricts blood supply to tumors, reduces metastasis and enhances effects of chemotherapies.
For the cardiovascular system, matrine prevents platelet aggregation, lowers lipids and blood pressure, improves circulation and protects the heart.
Purified matrine supplements ensure high potency and solve issues with inconsistent alkaloid content in plain herbs. Quality is verified through HPLC testing.
Certificate Of Analysis
Analysis | Specification | Results |
Assay（HPLC） | ≥98% | 98.17% |
Appearance | White Powder | Complies |
Odor | Characteristic | Complies |
Sulphated Ash | ≤1% | 0.4% |
Moisture | ≤5% | 4.3% |
Loss on drying | ≤5% | 3.8% |
Particle size | 95% pass 80 mesh | Complies |
PH | 9.5-10.5 | Complies |
Heavy metal | <10ppm | Complies |
Residue on ignition | 3% Max | 1.56% |
Total Plate Count | 1000/g Max | Complies |
Yeast & Mold | 100/g Max | Complies |
Escherichia coli | Negative | Negative |
Salmonella | Negative | Negative |
Functions
Decades of research have defined several key functions and mechanisms of action for matrine powder:
● Alleviates joint pain and protects cartilage in arthritis.
● Treats gastrointestinal ulcers and inflammation in colitis and gastritis.
● Clears infection and attenuates liver fibrosis in hepatitis patients.
● Inhibits cancer cell proliferation, metastasis and angiogenesis as an adjunct to chemotherapy.
● Protects heart function and prevents myocardial fibrosis after cardiac injury.
● Reduces severity of allergic reactions and stabilizes mast cells.
● Promotes nerve cell regeneration after injury to the optic nerve and spinal cord.
● Accelerates cutaneous wound healing and relieves skin inflammatory disorders like psoriasis.
● Stimulates red blood cell production to counteract anemia.
With broad pharmacological effects and mechanisms of action, high-purity matrine offers value for improving health and complementing conventional treatments.
Applications
In addition to pharmaceutical uses, matrine has found applications in the following industries:
Nutraceutical Industry – It is widely used in supplements for pain relief, liver health, seasonal allergies, immune enhancement, viral infections, and joint support.
Food Industry
Functional foods and beverages integrate matrine for its anti-inflammatory benefits in managing arthritis, diabetes complications, respiratory conditions, and digestive disorders.
Cosmetics Industry
Matrine demonstrates antioxidant activity to combat skin aging. It also accelerates wound healing for use in skin repair creams.
Animal Health
Matrine improves immunity and resistance in livestock animals against bacterial and viral diseases to support growth and production.
Agriculture
As a natural pesticide, matrine controls fungal crop diseases caused by Fusarium, Phytophthora, Rhizoctonia, and other plant pathogens.
With matrine’s diverse pharmacological effects, it holds potential for wider applications as a functional food ingredient, topical skin product component, veterinary anti-infective agent, and natural agricultural fungicide.
Flow Chart
Packing And Shipping
● Fast lead time, with a professional freight forwarder;
● Fast service response to customers' orders;
● 25kgs/drum, Double polyethylene bags inside, and high-quality standard carton drum outside.
Certificates
We have professional product certifications and technical invention patents, including Kosher certification, FDA certificate, ISO9001, PAHS Free, HAlAL, NON-GMO, SC.
Exhibition
We have participated in SUPPLYSIDE WEST. Our products are exported to more than 30 countries including the United States, India, Canada, Japan, and so on.
Our Factory
We have perfect and mature production technology. “Filter Tank Used In The Production Process of Resveratrol”, “Method of Producing Resveratrol with Fresh Polygonum Cuspidatum”, “High-Quality Low-Temperature Concentration Tank”, “Method of Preparing Resveratrol Extract by Microbial Fermentation Technology”, all of them have obtained national invention patents.
We are Matrine Powder manufacturers and suppliers, if you need please contact us at Email: nancy@sanxinbio.com.
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